Figure 4

Nematode-specific sequence features in the NF families. Insertions specific to nematodes were evident in the global multiple alignment among members of NF_0313_0956 and orthologous proteins from non-nematode species. NF_0313_0956 included SS00822 (Strongyloides stercoralis), 14968.m01483 (Brugia malayi), F45H10.3 (Caenorhabditis elegans), gi-39591288-emb-CAE73341.1-(Caenorhabditis briggsae), cr01.Contig9.wum.334.1 (Caenorhabditis remanei), AE04133 (Ancylostoma ceylanicum), HC05738 (Haemonchus contortus), NB03814 (Nippostrongylus brasiliensis), OS04039 (Ostertagia ostertagi), PT04092 (Parastrongyloides trichosuri), and MH00982 (Meloidogyne hapla). Non-nematode orthologous proteins were those annotated as the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 7 (KO: K03951) from fly, bovine, mouse, rat, and human.