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Table 4 Changes in SP localization prediction due to mutations.

From: Prediction of disease-related mutations affecting protein localization

 

Mutant compartment

Wild type compartmenta

Gtm

Mtm/Gtm

Mma/C

Mma

Mma/PM

Mps/S

C

Mma/P

N

PM

Mtm

S

Mtm/PM

Mma/N

P

Total

Mtm/Gtm

0/3

   

1/1

          

1/4

Mtm/PM

0/6

0/9

  

1/1

          

1/16

PM

17/47

     

0/1

     

4/5

  

21/53

S

0/4

        

7/8

     

7/12

C

0/1

 

8/8

     

19/20

1/1

 

1/1

  

0/2

29/33

Mtm

 

0/3

 

1/1

           

1/4

Mma/Gtm

 

0/2

             

0/2

Gtm

 

0/5

       

17/21

0/1

2/4

   

19/31

Mtm/C

  

0/1

1/4

           

1/5

Mps/C

  

1/1

            

1/1

Mma

  

6/6

  

1/1

2/2

1/1

       

10/10

Mma/S

  

2/2

1/1

 

1/1

         

4/4

Mma/C

      

4/4

        

4/4

Mps

     

2/2

         

2/2

Mma/N

      

1/1

 

1/1

      

2/2

P

        

1/1

      

1/1

N

         

0/18

   

1/1

 

1/19

Total

17/61

0/19

17/18

3/6

2/2

4/4

7/8

1/1

21/22

25/48

0/1

3/5

4/5

1/1

0/2

105/203

  1. The numbers separated by the slash sign are for how many proteins the wild type localization has been correctly predicted, and the number of analyzed mutations, respectively.
  2. aC, cytosol; Gtm, Golgi, transmembrane; Mma, mitochondrial matrix; Mps, mitochondrial, periplasmic space; Mtm, mitochondrial transmembrane; N, nuclear; P, peroxisomal; PM, plasma membrane; S, secreted. Slash sign indicates alternative predicted localizations.
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BMC Genomics

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