Table 4 Overlapping genes identified by expression and fitness profiling approaches under iron-limited conditions
Gene ID | Gene Name | Log2 expression | Log2 fitness | Protein function | Cellular localization |
|---|---|---|---|---|---|
YCR007C 1 | Â | 0.47 | -0.98 | Unknown | Plasma membrane |
YMR058W 1 | FET3 | 0.76 | -3.85 | Multicopper oxidase | Plasma membrane |
YLR214W 1 | FRE1 | 0.93 | -2.21 | Ferric (and cupric) reductase | Plasma membrane |
YKR052C 1 | MRS4 | 0.50 | -3.55 | Mitochondrial carrier protein | Mitochondria |
YJL094C 1 | KHA1 | 0.40 | -2.51 | Putative H+/K+ antiporter | Membrane |
YHL027W 1 | RIM101 | 0.76 | -2.64 | Transcriptional activator required for meiosis | Nucleus |
YDR271C 1 | Â | 0.82 | -2.56 | Unknown, overlaps CCC2 | Unknown |
YDR270W 1 | CCC2 | 0.63 | -1.65 | P-type ATPase | Golgi apparatus |
YPL182C 2 | Â | -0.29 | -3.65 | Cyc8-Tup1 interacting protein | Nucleus |
YPL170W 2 | DAP1 | -0.32 | -4.33 | Regulator of Erg11 | Membrane |
YGR270W 2 | YTA7 | -1.54 | -1.52 | ATPase activity | Unknown |
YLR304C 3 | ACO1 | -0.82 | 1.03 | Aconitase (TCA cycle) | Mitochondria |