| Gene Number |
---|
Subfamily | Human | Mouse | Cow |
---|
IFNK | 1 | 1 | 1 |
IFNE | 1 | 1 | 1 |
IFNB | 1 | 1 | 6 |
IFND | 0 | 0 | 0 |
IFNZ | 0 | 2 | 0 |
IFNA | 13 | 14 | 13 |
IFNW | 1 | 0 | 24 |
IFNT | 0 | 0 | 3 |
IFNX | 0 | 0 | 3 |
IFNL | 3 | 3 | 0 |
- The number of predicted IFN genes in each subfamily based on genomic analysis of the mouse, human, and bovine are shown. Predicted pseudogenes based on frameshift mutations or stop codons within the first 100 aa of the coding sequence have been excluded from the table. The bovine Type I IFN locus has an expansion of both the IFNB and IFNW subfamilies. Cattle have also acquired two novel IFN subfamilies, IFNT and a previously unidentified IFN family, termed IFNX, discovered during this analysis.