Table 6 Genes with putative cummulative downregulation in blastocysts obtained after serial rounds of chromatin tranfer
From: Transcriptional reprogramming of gene expression in bovine somatic cell chromatin transfer embryos
Probe Set ID | Gene Title | Gene Symbol | IVF | CT1 | CT4 | Fold change IVF/CT1 | Fold change IVF/CT4 |
|---|---|---|---|---|---|---|---|
Bt.5154.1.S1_at | heat shock 70 kD protein 1 | HSPA1A | 16655.53 | 4021.00 | 2975.26 | 4.14 | 5.60 |
Bt.9759.1.S1_a_at | neuroguidin, EIF4E binding protein | NGDN | 11691.84 | 5346.60 | 3041.70 | 2.19 | 3.84 |
Bt.5039.1.S1_at | high mobility group nucleosomal binding domain 3 | HMGN3 | 11195.32 | 6522.85 | 4078.53 | 1.72 | 2.74 |
Bt.9759.2.S1_at | neuroguidin, EIF4E binding protein | NGDN | 5999.87 | 2431.02 | 1665.35 | 2.47 | 3.60 |
Bt.4737.1.S2_s_at | prion protein | PRNP | 3552.73 | 1614.40 | 1425.30 | 2.20 | 2.49 |
Bt.1854.1.S1_at | intraflagellar transport protein 20 | IFT20 | 3526.47 | 2139.25 | 1380.10 | 1.65 | 2.56 |
Bt.27874.1.S1_s_at | phosphatidylserine receptor | PTDSR | 3476.73 | 1517.25 | 980.58 | 2.29 | 3.55 |
Bt.15787.1.S1_at | Bcl-2 inhibitor of transcription | BIT1 | 2989.58 | 2007.15 | 1415.27 | 1.49 | 2.11 |
Bt.20204.1.S1_at | Sjogren's syndrome/scleroderma autoantigen 1 | SSSCA1 | 1695.08 | 1056.05 | 579.62 | 1.61 | 2.92 |
Bt.4595.1.S1_at | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | TSR2 | 1567.39 | 755.35 | 568.11 | 2.08 | 2.76 |
Bt.12250.1.S1_at | chromosome 14 open reading frame 10 | C14orf10 | 1525.13 | 981.80 | 567.59 | 1.55 | 2.69 |
Bt.27095.1.S1_at | collaborates/cooperates with ARF (alternate reading frame) protein | CARF | 1390.25 | 907.40 | 668.85 | 1.53 | 2.08 |
Bt.13928.2.S1_a_at | sodium channel modifier 1 | SCNM1 | 786.05 | 390.50 | 249.35 | 2.01 | 3.15 |
Bt.6620.1.S1_at | myosin, heavy polypeptide 7, cardiac muscle, beta | MYH7 | 673.53 | 219.15 | 135.85 | 3.07 | 4.96 |
Bt.19972.1.S1_at | proton-dependent gastrointestinal peptide transporter | PEPT1 | 567.85 | 189.46 | 170.27 | 3.00 | 3.34 |
Bt.28010.1.S1_at | protease inhibitor 3, skin-derived (SKALP) | PI3 | 510.98 | 91.50 | 56.05 | 5.58 | 9.12 |
Bt.5126.1.S1_at | hypertension-related calcium-regulated gene | COMMD5 | 449.40 | 335.50 | 176.24 | 1.34 | 2.55 |
Bt.22523.1.S1_at | dispatched homolog 1 (Drosophila) | DISP1 | 402.17 | 174.75 | 155.13 | 2.30 | 2.59 |
Bt.5828.1.S1_at | SERTA domain containing 1 | SERTAD1 | 357.71 | 287.95 | 157.44 | 1.24 | 2.27 |
Bt.333.1.S1_at | transition protein 1 (during histone to protamine replacement) | TNP1 | 233.38 | 155.00 | 98.93 | 1.51 | 2.36 |
Bt.14098.1.S1_at | microtubule-associated protein, RP/EB family, member 2 | MAPRE2 | 199.89 | 183.45 | 69.82 | 1.09 | 2.86 |
Bt.4158.1.A1_at | oviduct specific glycoprotein | OVGP1 | 196.48 | 168.70 | 78.09 | 1.16 | 2.52 |
Bt.22856.1.S1_at | neurofilament, medium polypeptide | NEF3 | 188.69 | 126.35 | 46.89 | 1.49 | 4.02 |
Bt.9807.1.S1_at | glycoprotein (transmembrane) nmb | GPNMB | 154.95 | 52.30 | 24.03 | 2.96 | 6.45 |
Bt.23151.1.S1_at | fucosyltransferase 10 (alpha (1,3) fucosyltransferase) | FUT10 | 154.43 | 114.10 | 55.12 | 1.35 | 2.80 |
Bt.7239.1.S1_at | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | SLC6A3 | 149.32 | 48.30 | 21.24 | 3.09 | 7.03 |
Bt.12739.2.S1_a_at | membrane-associated ring finger (C3HC4) 2 | C3HC4 | 110.18 | 51.40 | 23.87 | 2.14 | 4.62 |
Bt.6556.1.S1_at | regakine-1 protein | LOC504773 | 89.66 | 25.75 | 39.07 | 3.48 | 2.29 |
Bt.12080.2.S1_at | Bernardinelli-Seip congenital lipodystrophy 2 | BSCL2 | 88.59 | 38.70 | 13.83 | 2.29 | 6.41 |
Bt.13036.1.S1_at | progesterone receptor | PGR | 79.73 | 4.69 | 36.57 | 17.02 | 2.18 |
Bt.2157.1.S1_a_at | RPGR-interacting protein 1 | RPGRIP1 | 77.03 | 58.90 | 6.56 | 1.31 | 11.75 |
Bt.28409.2.S1_at | DNA replication factor | CDT1 | 71.69 | 55.20 | 12.73 | 1.30 | 5.63 |
Bt.3771.1.A1_at | Nucleolar protein family A, member 1 | NOLA1 | 69.73 | 21.50 | 21.26 | 3.24 | 3.28 |
Bt.27752.1.S1_at | tensin 4 | TNS4 | 69.66 | 43.05 | 8.73 | 1.62 | 7.98 |
Bt.13024.2.S1_at | purinergic receptor P2Y G-protein coupled, 2 | P2RY2 | 67.08 | 46.15 | 22.11 | 1.45 | 3.03 |
Bt.28017.1.S1_at | vacuolar H+-ATPase | LOC407191 | 65.07 | 34.20 | 17.47 | 1.90 | 3.73 |
Bt.512.1.S1_at | nucleotide phosphodiesterase, 3'-5'-cyclic | PDE1A | 60.70 | 15.59 | 15.85 | 3.89 | 3.83 |
Bt.12928.1.S1_at | Interleukin 13 | IL13 | 58.85 | 37.70 | 9.25 | 1.56 | 6.36 |
Bt.29129.1.S1_at | anterior gradient 2 homologue | agr2 | 45.07 | 39.00 | 21.29 | 1.16 | 2.12 |