Figure 10

Comparison of recombination signal sequences of human, murine and bovine TRB genes. Sequence logos for the RSs of (A) TRBV and (B) TRBJ genes of bovine, humans and mice. The heptamer and nonamer sequences are enclosed in boxes. The height of the letters is correlated to their conservation at each location. (C) Consensus sequences of RSs from the different groups of bovine, human and murine TRB genes. Dashes represent nucleotide identity. M = A/C, R = A/G, W = A/T, and Y = C/T. Non-functional RSs functional have been excluded from the analysis.