Figure 1
From: Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells
The number of differentially expressed probe-sets in Itk-deficiency. a. Venn diagram showing overlapping probe-sets in CD3+ Itk-defective T-cells, unstimulated (upper), anti-CD3- (left) and anti-CD3/CD28-stimulated (right). All the comparisons were made against Wt and with the criterion ≥ 2-fold. b. Quantitative RT-PCR confirms up-regulated expression of Klra3, Klra7 and Klrg1 in Itk-deficiency. The bar charts show relative amount of Klr mRNA compared to unstimulated Wt CD3+ T-cells (Wt C).