Figure 2From: Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3Overview of the pathways involved in energy generation in BmL3i. The red arrows and numbers indicate increased levels of enzymatic activity as inferred by fold changes in gene expression. ETC: electron transport chain; Q: electron carrier. The numbers in parentheses are fold changes: 1, isocitrate dehydrogenase-EC 1.1.1.42: 14990.m07912 (3 fold); 2, succinate-ubiquinone oxidoreductase – EC 1.3.5.1: BMC09915 (3 fold)and WB-contig_1179 (4.3); 3, malate dehydrogenase – EC 1.1.1.37: BMC05093 (3 fold), BMC11994 (4 fold); 4, NADH dehydrogenase (ubiquinone): – EC1.6.5.3: there are four elements encoding the enzyme – BMC07652 (3.3 fold), TC3428 (2.9 fold), BMC04790 (4 fold) and 14062.m00071(2.6 fold); 5, Ubiquinol – cytochrome-c reductase or Cytochrome bc1 complex – EC 1.10.2.2: WB-contig_1179 (4.3); 6, Cytochrome c oxidase-EC 1.9.3.1: BMC06398 (2.7); 7, ATP synthase-EC 3.6.3.14: 14980.m02712 (3.4), 14982.m02237 (3.3) and WB-contig_234 (2); 8, Pyruvate dehydrogenase complexes-EC 1.2.4.1: BMC08144 (4.3) and WB-contig_1351 (5.4); 9, Acetyl-CoA C-acyltransferase-EC 2.3.1.16: TC3583 (6.2); 10, Acetyl-coenzyme A synthetase-EC 6.2.1.1: BMC03124 (2.6).Back to article page