Table 1 Candidate genes induced by acute cellular rejection relative to the strain effect in peripheral blood mononuclear cells
From: Impact of animal strain on gene expression in a rat model of acute cardiac rejection
Gene Title | Gene Symbol | Entrez Gene | Strain+Rejection Effect FC | Strain Effect FC | Strain+Rejection /Strain FC | p-value |
|---|---|---|---|---|---|---|
ring finger protein (C3H2C3 type) 6 (predicted) | Rnf6_predicted | 304271 | 0.40 | 0.01 | 40.54 | 1.44E-11 |
membrane-spanning 4-domains, subfamily A, member 7 (predicted) | Ms4a7_predicted | 293744 | 0.91 | 0.03 | 31.66 | 2.07E-03 |
S100 calcium binding protein A9 (calgranulin B) | S100a9 | 94195 | 3.55 | 0.32 | 11.05 | 2.63E-03 |
complement component 1, q subcomponent, gamma polypeptide | C1qg | 362634 | 4.07 | 0.46 | 8.84 | 7.39E-03 |
distrobrevin binding protein 1 | Dtnbp1 | 641528 | 0.75 | 0.10 | 7.61 | 1.36E-04 |
matrix metallopeptidase 14 (membrane-inserted) | Mmp14 | 81707 | 4.22 | 0.59 | 7.19 | 3.83E-03 |
Thyroid hormone receptor associated protein 6 (predicted) | Thrap6_predicted | 299905 | 0.27 | 0.04 | 7.09 | 1.25E-03 |
myxovirus (influenza virus) resistance 2 | Mx2 | 286918 | 0.09 | 0.02 | 5.88 | 3.09E-05 |
prolylcarboxypeptidase (angiotensinase C) (predicted) | Prcp_predicted | 293118 | 1.02 | 0.21 | 4.89 | 1.53E-04 |
2',5'-oligoadenylate synthetase 1, 40/46 kDa | Oas1 | 192281 | 1.33 | 0.28 | 4.69 | 1.33E-06 |
high mobility group box 1 | Hmgb1 | 25459 | 0.68 | 0.17 | 3.92 | 1.21E-07 |
COX15 homolog, cytochrome c oxidase assembly protein (yeast) | Cox15 | 309391 | 0.87 | 0.23 | 3.87 | 1.92E-05 |
RT1 class II, locus Ba | RT1-Ba | 309621 | 0.60 | 0.17 | 3.60 | 3.23E-04 |
complement factor B | Cfb | 294257 | 0.91 | 0.27 | 3.40 | 4.27E-04 |
interferon induced transmembrane protein 3 | Ifitm3 | 361673 | 0.89 | 0.27 | 3.22 | 1.86E-04 |
interferon-induced protein with tetratricopeptide repeats 3 | Ifit3 | 309526 | 0.35 | 0.11 | 3.11 | 4.13E-03 |
granzyme B | Gzmb | 171528 | 0.64 | 0.21 | 3.02 | 1.87E-04 |
granzyme A | Gzma | 266708 | 0.70 | 0.23 | 3.00 | 4.25E-04 |