Figure 4

Comparison of tissue expression ratios from transcriptomic and proteomic profiling. Pair-wise comparison of heart-muscle log2 expression ratios obtained by 454-sequencing, cDNA microarray and iTRAQ-based proteomics for 148 genes detectable by all three technologies. Thick lines represent fitted straight lines from the data points. The distances between the thick and thin lines are equal to one time the standard deviation of all distances from data points to the fitted lines. The black data points between the two thin lines were considered to represent genes where transcript and protein ratios are in concordance, whereas the outside red data points were considered to represent genes where transcript and protein ratios are not in concordance (red).