Figure 1

Network Connection Strength Versus Expression Correlation. Network adjacency (y-axis) versus correlation (x-axis) for an unweighted network (black step function with τ = 0.8) and weighted networks (dashed lines corresponding to different powers, β) in an unsigned network (a) and a signed network (b). Note that cor(x _i , x _j ) = -1 leads to adjacency = 0 in the signed network. The weighted network preserves the continuous nature of the co-expression information while an unweighted network dichotomizes the correlation.