Skip to main content
Figure 3 | BMC Genomics

Figure 3

From: Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling

Figure 3

a-b. qPCR and exon-level assessment of gene knockdown by siRNA. 3a. Percentage mRNA knock-down 48 hours after siRNA transfection compared to a control siRNA tagetting the control gene Lamp1. 3b. Example of gene knock-down by exon array analysis. Level of knock-down at each of the 23 exon probesets across the entire length of the Nfkb2 transcript in the presence of IFNγ. The green line represents the median signal intensity in the three control arrays (RISC-Free) and red line the median signal intensity in the three Nfkb2 siRNA knock-down arrays (for other exon-level results see Additional file 3).

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us