Figure 4

Example where CGHnormaliter achieves better results than popLowess due to more sophisticated clustering of the intensity ratios. Calling results on a GIST tumor sample (sample 57) after (A) popLowess and (B) CGHnormaliter normalization are shown. FISH analyses revealed losses in 2 chromosomes (14 and 15). All losses are identified largely by both methods but CGHnormaliter scores better in specificity and precision. The figure format is explained under Figure 3.