A microarray analysis of sex- and gonad-biased gene expression in the zebrafish: Evidence for masculinization of the transcriptome

Table 2 Expression bias and increasing fold change threshold

Expression bias class	No fold threshold	≥ 1.5 fold	≥ 2 fold	≥ 4 fold	≥ 6 fold
Male-enriched	3387	3219	2576	1196	728
Female-enriched	2512	2281	1684	664	413
Testis-upregulated	3002	2824	2159	925	554
Ovary-upregulated	981	842	426	0	0

Number of sex- and gonad-biased genes (strict consensus FDR = 0.05) under increasing fold change thresholds. As the fold change criterion becomes more stringent, fewer genes are deemed differentially expressed, but the male-biased patterns remains consistent. The numbers above reflect genes that satisfy the indicated fold change thresholds across all four absolute expression analyses.

ISSN: 1471-2164