Table 5 Significantly regulated genes in mono-transgenic dnADAM10 mice in relation to FVB/N wild-type mice
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Gene ID | Gene symbol | Description | Fold change | log ratio | d-value | Functional groups |
|---|---|---|---|---|---|---|
22589 | Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 1.392 | 0.477 | 1.533 | nervous system development |
109880 | Braf | Braf transforming gene | 0.568 | -0.815 | -5.060 | cell communication |
54598 | Calcrl | calcitonin receptor-like | 0.626 | -0.675 | -2.137 | cell communication |
12322 | Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.686 | -0.544 | -2.523 | cell communication; receptor binding and activity; synapse |
12772 | Ccr2 | chemokine (C-C motif) receptor 2 | 0.724 | -0.465 | -1.783 | cell communication |
16149 | Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 0.737 | -0.441 | -2.329 | cell communication; cell death |
13175 | Dcamkl1 | doublecortin and calcium/calmodulin-dependent protein kinase-like 1 | 1.501 | 0.586 | 1.610 | nervous system development |
12140 | Fabp7 | fatty acid-binding protein 7 | 1.691 | 0.758 | 2.107 | nervous system development |
14281 | Fos | FBJ osteosarcoma oncogene | 0.669 | -0.58 | -1.805 | nervous system development |
14417 | Gad2 | glutamic acid decarboxylase 2 | 1.422 | 0.508 | 1.683 | cell communication; neuron projection; synapse |
14674 | Gna13 | guanine nucleotide binding protein, alpha 13 | 1.353 | 0.436 | 1.639 | cell communication |
14682 | Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 1.323 | 0.404 | 1.621 | cell communication; nervous system development; synapse |
15557 | Htr1f | 5-hydroxytryptamine (serotonin) receptor 1F | 1.363 | 0.447 | 1.539 | cell communication |
16594 | Klc2 | kinesin light chain 2 | 0.789 | -0.341 | -1.485 | neuron projection |
207911 | Mchr1 | melanin-concentrating hormone receptor 1 | 0.718 | -0.477 | -3.057 | cell communication |
17260 | Mef2c | myocyte enhancer factor 2C | 1.433 | 0.519 | 1.507 | nervous system development |
18823 | Plp1 | proteolipid protein (myelin) 1 | 1.358 | 0.442 | 1.565 | cell communication; nervous system development; |
19293 | Pvalb | parvalbumin | 0.847 | -0.24 | -1.493 | neuron projection |
19317 | Qk | quaking | 1.312 | 0.392 | 1.522 | cell communication; nervous system development |
54409 | Ramp2 | receptor (calcitonin) activity modifying protein 2 | 1.604 | 0.682 | 1.623 | cell communication |
19736 | Rgs4 | regulator of G-protein signaling 4 | 1.339 | 0.421 | 1.843 | cell communication |
20202 | S100a9 | S100 calcium binding protein A9 | 0.696 | -0.522 | -2.181 | cell communication |