Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis

Lebo, Matthew S; Sanders, Laura E; Sun, Fengzhu; Arbeitman, Michelle N

doi:10.1186/1471-2164-10-80

BMC Genomics

Table 2 Sex differentially expressed genes in somatic tissues during metamorphosis.

From: Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis

Hr APF	Sex-bias	Gene Name	CG # *	Ch^†	FC^‡	Functional Annotation^ξ
0 hr	Male	RNA on the X 1	CR32777	X	24.1	dosage compensation
		CG1441	CG1441	2R	2.5	catalytic activity; binding
	Female	CG4500	CG4500	2L	2.7	mesoderm development
		Larval serum protein 1 α	CG2559	X	2.3	nutrient reservoir activity; oxygen transporter
		Transferrin 1	CG6186	X	2.0	iron ion transport; defense response
24 hr	Male	RNA on the X 1	CR32777	X	150.6	dosage compensation
		dusky	CG9355	X	16.1	wing morphogenesis
		CG1368	CG1368	X	5.0	structural constituent of chorion
		CG5823	CG5823	3R	4.9	ubiquitin-protein ligase activity
		CG31948	CG31948	2L	3.8	protein modification process
		CG4691	CG4691	2L	3.6	unknown
		Cyto dynein light chain 2	CG5450	2L	3.5	microtubule motor activity
		CG11350	CG11350	3L	3.2	unknown
		CG6372	CG6372	3L	3.0	mushroom body development; proteolysis
		CG10383	CG10383	2L	2.6	binding
		Moesin	CG10701	X	2.2	cytoskeletal protein binding; actin binding
		CG2082	CG2082	3R	2.2	unknown
		CG11905	CG11905	3L	2.2	hydrolase activity
		Cuticular protein 12A	CG15757	X	2.0	structural constituent of cuticle
		Mov34	CG3416	2R	2.0	endopeptidase activity; cell proliferation
	Female	CG2930	CG2930	X	4.1	oligopeptide transport
		CG10650	CG10650	2L	3.2	oxidoreductase activity
		CG12290	CG12290	3R	2.4	G-protein coupled receptor activity
		CG14540	CG14540	3R	2.4	unknown
		CG16997	CG16997	2L	2.3	serine-type endopeptidase activity
		CG7045	CG7045	3R	2.3	regulation of transcription; DNA binding
		CG9634	CG9634	X	2.3	metalloendopeptidase activity
		white	CG2759	X	2.3	transmembrane receptor activity; eye pigment
		26–29 kD-proteinase	CG8947	3L	2.3	cathepsin K activity; proteolysis
		CG32695	CG32695	X	2.3	unknown
		ion transport peptide	CG13586	2R	2.2	neuropeptide hormone activity
		CG15312	CG15312	X	2.1	unknown
		CG15369	CG15369	X	2.1	cysteine protease inhibitor activity
		CG16865	CG16865	2L	2.0	unknown
48 hr	Male	RNA on the X 1	CR32777	X	232.8	dosage compensation
		CG31988	CG31988	2L	5.2	zinc ion binding
		bangles and beads	CG7088	X	2.3	gliogenesis
		CG1368	CG1368	X	2.3	structural constituent of chorion
		CG9914	CG9914	X	2.0	fatty acid metabolic process
		CG31948	CG31948	2L	2.0	protein modification process
	Female	Cuticular protein 12A	CG15757	X	5.0	structural constituent of cuticle
		Hs protein cognate 2	CG7756	3R	5.0	unfolded protein binding; ATP binding
		CG6416	CG6416	3L	3.6	mesoderm development; protein binding
		CG1441	CG1441	2R	3.5	catalytic activity; binding
		CG12523	CG12523	3L	3.1	unknown
		Mec2	CG7635	X	2.8	unknown
		CG32982	CG32982	2L	2.8	unknown
		CG8745	CG8745	3L	2.6	arginine catabolic process to glutamate
		gonadal	CG33756	3L	2.5	spermatogenesis; oogenesis
		CG12009	CG12009	3L	2.5	chitin binding; chitin metabolism
		Larval serum protein 1 α	CG2559	X	2.4	nutrient reservoir activity; oxygen transporter
		CG7367	CG7367	2L	2.3	phagocytosis; lipid metabolic process
		CG15369	CG15369	X	2.2	cysteine protease inhibitor activity
		CG31901	CG31901	2L	2.2	unknown
		CG13360	CG13360	X	2.1	unknown
		CG10589	CG10589	3L	2.1	unknown
72 hr	Male	RNA on the X 1	CR32777	X	147.6	dosage compensation
		CG7191	CG7191	2L	2.1	unknown
		Verprolin 1	CG13503		2.1	actin filament organization
	Female	CG11591	CG11591	3L	6.2	unknown
		CG31948	CG31948	2L	5.5	protein modification process
		CG32690	CG32690	X	5.1	unknown
		CG7738	CG7738		4.0
		CG10589	CG10589	3L	3.8	unknown
		CG9975	CG9975	2R	3.7	unknown
		Cuticular protein 12A	CG15757	X	3.7	structural constituent of cuticle
		CG31639	CG31639	2L	3.3	unknown
		CG4691	CG4691	2L	3.1	unknown
		Jonah 25Biii	CG8871	2L	3.1	elastase activity; serine-type endopeptidase
		CG7322	CG7322	X	3.0	oxidoreductase activity
		Lysozyme B	CG1179	3L	2.9	lysozyme activity
		CG17118	CG17118	2L	2.6	dendrite morphogenesis
		CG8813	CG8813	2L	2.6	unknown
		CG13360	CG13360	X	2.4	unknown
		CG10809	CG10809	3L	2.4	unknown
		CG5446	CG5446	2L	2.4	unknown
		CG14540	CG14540	3R	2.3	unknown
		Peroxiredoxin 2540	CG11765	2R	2.3	glutathione peroxidase activity
		CG31901	CG31901	2L	2.2	unknown
		abdominal A	CG10325	3R	2.2	transcription factor; organismal development
		CG15369	CG15369	X	2.1	cysteine protease inhibitor activity
		Larval serum protein 1 α	CG2559	X	2.1	nutrient reservoir activity; oxygen transporter
		CG12250	CG12250	3R	2.1	unknown
		CG17244	CG17244	3R	2.0	unknown
		CG1998	CG1998	X	2.0	C-4 methylsterol oxidase activity
96 hr	Male	RNA on the X 1	CR32777	X	325.5	dosage compensation
		CG31988	CG31988	2L	7.8	zinc ion binding
		CG6372	CG6372	3L	5.7	mushroom body development; proteolysis
		Cyt. dynein light chain 2	CG5450	2L	4.1	microtubule motor activity
		charlatan	CG11798	2R	4.1	nervous system development; transcription
		CG17829	CG17829	X	3.8	zinc ion binding
		CG1774	CG1774	3R	3.7	catalytic activity; nucleotide binding
		CG31029	CG31029	3R	3.6	unknown
		Syntaxin Interact. Prot. 2	CG13164	2R	3.5	unknown
		Lysozyme B	CG1179	3L	3.3	lysozyme activity
		CG4691	CG4691	2L	3.3	unknown
		carmine	CG3035	X	3.1	neurotransmitter secretion; synaptic vesicle
		CG4300	CG4300	3L	2.7	spermidine synthase activity
		peste	CG7228	2L	2.7	scavenger receptor activity
		dacapo	CG1772	2R	2.7	cyclin-dependent protein kinase inhibitor
		CG8813	CG8813	2L	2.6	unknown
		Ribosomal protein S5b	CG7104	3R	2.4	structural constituent of ribosome
		CG12237	CG12237	X	2.4	phosphoric monoester hydrolase activity
		CG7738	CG7738		2.4	unknown
		CG9975	CG9975	2R	2.3	unknown
		CG17180	CG17180	3L	2.3	vesicle-mediate transport
		CG12009	CG12009	3L	2.2	chitin binding
		CG8931	CG8931	X	2.2	binding; transport
		CG17230	CG17230	3R	2.2	unknown
		CG31163	CG31163	3R	2.1	SH3/SH2 adaptor activity
		epsilonCOP	CG9543	2L	2.1	retrograde vesicle-mediated transport
		CG30392	CG30392	2R	2.1	glycolipid transporter activity
		CG31639	CG31639	2L	2.1
		CG5343	CG5343	2L	2.0	muscle development; dendrite morphogenesis
		CG4845	CG4845	3R	2.0	phagocytosis; immune response
		Hs protein cognate 2	CG7756	3R	2.0	unfolded protein binding; ATP binding
	Female	CG1368	CG1368	X	3.9	structural constituent of chorion
		Larval serum protein 1 α	CG2559	X	3.0	nutrient reservoir activity; oxygen transporter
		Arginine kinase	CG32031	3L	3.0	arginine kinase activity
		CG15369	CG15369	X	2.4	cysteine protease inhibitor activity
		CG32695	CG32695	X	2.4	unknown
		CG7816	CG7816	3R	2.3	metal ion transmembrane transporter
		white	CG2759	X	2.2	transmembrane receptor activity; eye pigment
		CG32850	CG32850	4	2.1	protein binding; zinc ion binding
		CG14717	CG14717	3R	2.0	hydrolase activity
		CG17118	CG17118	2L	2.0	dendrite morphogenesis

Significant somatic, sex-differential expression determined using F-tests, and a t-test of means comparing expression data from male and female tud progeny. All genes listed had at least a 2-fold difference in transcript abundance between the sexes. For the full lists of sex-differentially expressed genes, see Additional file 3. * Annotation symbol from Flybase. ^† Chromosomal arm on which the gene is located. ^‡ Fold change difference between the sexes. ^ξGO annotations for each gene as listed in Flybase.

Back to article page

ISSN: 1471-2164

Contact us

Submission enquiries: bmcgenomics@biomedcentral.com
General enquiries: ORSupport@springernature.com