DNA-binding residues and binding mode prediction with binding-mechanism concerned models

BMC Genomics

Table 4 Performance delivered by alternative predictors of DNA-binding residues, where the F-measure is the harmonic mean of precision and sensitivity

Predictor	Sensitivity	Specificity	Accuracy	Precision	F-measure
Sequence-specific binding	0.501	0.993	0.965	0.817	0.622
Non-specific binding	0.530	0.953	0.891	0.655	0.586
Specific+Non-specific	0.569	0.956	0.893	0.719	0.635
Ahmad and Sarai[10]	0.682	0.660	0.664	0.308*	0.425*
Yan et al.[8]	0.410	0.871	0.780	0.439*	0.424*
BindN (Wang and Brown)[40]	0.652	0.728	0.722	0.186*	0.289*
DP-Bind (Hwang et al.)[7]	0.791	0.786	0.800	-*	-*

*The numbers with an asterisk are those that have been derived from the numbers reported in the related studies.

ISSN: 1471-2164