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Figure 3 | BMC Genomics

Figure 3

From: Pediatric primary central nervous system germ cell tumors of different prognosis groups show characteristic miRNome traits and chromosome copy number variations

Figure 3

Altered functional modules in the different pediatric GCT prognostic groups. (A-B) Gene set enrichment analysis according to the Gene Ontology (GO) classification. Probe sets differentiating good prognostic CNS GCTs from intermediate/poor prognostic CNS GCTs were subjected to the GO database search via the DAVID 2008 interface. The number of genes, gene symbols, their percentages and the p values for each category that show significance (p < 0.05) and are enriched in either the good (A) or the intermediate/poor (B) prognostic group are listed. (C) KEGG pathways significantly enriched in the TW NGMGCT genes. The number of genes, their percentages in terms of total genes, and the p values for pathways that are significantly over-represented (p < 0.05 by the DAVID 2008 tool) are listed. (D) Distribution of signature genes on the chromosome cytobands.

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BMC Genomics

ISSN: 1471-2164

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