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Figure 4 | BMC Genomics

Figure 4

From: Molecular and evolutionary characteristics of the fraction of human alpha satellite DNA associated with CENP-A at the centromeres of chromosomes 1, 5, 19, and 21

Figure 4

A) Schematic representation of the centromeric regions of chromosomes 1, 5 and 19. The three chromosomes share an alphoid array where the active centromere normally forms: D1Z7, D5Z2, and D19Z3 (15). As shown by Finelli et al (14), D1Z7 is embedded within D1Z5. Chromosomes 5 and 19 share a second alphoid array: D5Z1 and D19Z1. In situ hybridization with both pZ5.1 DNA (green signal) and BAC RP11-483B6 DNA (red signal) as probes on chromosomes in prometaphase (B, D) and nuclei (C).

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BMC Genomics

ISSN: 1471-2164

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