Figure 3
From: Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor
Correlation between predicted flux and observed gene expression. The histogram shows the correlation between gene expression and predicted flux for 549 enzyme-coding genes. A large number of enzyme-coding genes show high correlation. They include many primary metabolism genes and antibiotic biosynthesis genes. About half of the genes show poor correlation; these are mostly genes that show constant gene expression and/or predicted flux across the entire time course, leading to a correlation coefficient close to zero. A small but noteworthy number of genes show statistically significant negative correlation between gene expression levels and predicted flux. These cases are discussed in more detail in the main text.