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Table 3 Classification of transcripts associated with blood feeding function

From: An insight into the sialome of Glossina morsitans morsitans

Class

Number of ESTs

Enzymes

 

   Nucleotide catabolism

 

Endonuclease

3285

Rnase

19

Exonuclease 3'5' and 5'3'

28

5' nucleotidase/apyrase

44

Cimex-type apyrase (1)

2

Adenosine deaminase

46

   Serine proteases (2)

54

   Other proteases

10

   Esterases and lipases

42

   Lysosomal type phosphatase (1)

7

   NO synthase

25

   Oxidant metabolism

6

   Possible PGE2 synthase

2

   Hyaluronidase

2

Mucins

69

Antigen 5 family

66

Yellow protein family

5

Immunity related

 

   Alpha2 macroglobulin/TEP

15

   Pattern-recognition

 

Ficolins

197

C type lectins and galectins

49

Peptidoglycan binding protein

8

   Defense response peptide

7

   Similar to Drosophila virus induced peptide

13

   Stomoxyn antimicrobial family

6

Protease inhibitor domains

 

   Anti thrombin peptide

1

   Kunitz domain of serine protease inhibitor

1

   Serpins

21

Low complexity families of secreted peptides

 

   Glycine rich family

24

   Acidic proteins, probably secreted

40

Secreted proteins of conserved families

8

Secreted uncharacterized families

120

Possibly secreted proteins of unknown family (3)

360

Total

4582

  1. (1) probably cellular
  2. (2) possibly involved in phenol oxidase activation - may also be involved in cleavage of host proteins
  3. (3) At least one orf has signal peptide - most probably are UTR's of mRNAs