Transcriptome response to pollutants and insecticides in the dengue vector Aedes aegypti using next-generation sequencing technology

Table 2 Genes and clusters differentially transcribed after xenobiotic exposure

Genes/clusters differentially transcribed	Copper		Fluo		Atraz		Propo		Perm		Imida
	N	%	N	%	N	%	N	%	N	%	N	%
Total genes and additional clusters	71	0.61	141	1.20	98	0.84	462	3.94	31	0.26	361	3.08
Total genes	49	0.72	86	1.26	60	0.88	318	4.64	20	0.29	239	3.49
Over-transcribed	46	0.67	50	0.73	25	0.36	130	1.90	16	0.23	113	1.65
Under-transcribed	3	0.04	36	0.53	35	0.51	188	2.74	4	0.06	126	1.84
Total additional clusters not within genes	22	0.45	55	1.13	38	0.78	144	2.96	11	0.23	122	2.51
Over-transcribed	18	0.37	36	0.74	21	0.43	53	1.09	9	0.18	51	1.05
Under-transcribed	4	0.08	19	0.39	17	0.35	91	1.87	2	0.04	71	1.46

For each treatment, the number (N) of genes and additional clusters not mapped within predicted genes found significantly differentially transcribed are indicated. For each value, the associated percentage regarding the total number of genes (6850), the total number of clusters not mapped within predicted genes (4868), or the total of genes and additional clusters (11718) is indicated. Genes or clusters were considered significantly differentially transcribed comparatively to controls if their associated P value (Fisher's test) was < 0.001 after multiple testing corrections. Copper: exposed to copper sulfate; Fluo: exposed to fluoranthene; Atraz: exposed to atrazine; Propo: exposed to propoxur; Perm: exposed to permethrin; Imida: exposed to imidacloprid.

ISSN: 1471-2164