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Table 4 CGD metabolic pathways that show evidence of gene clustering.

From: Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser

 

#Genes

SC5314

WO1

Cdub

Ctro

Cpar

Lelo

Dhan

Psti

Pgui

Clus

Histidine, purine and pyrimidine biosynthesis

41

7

7

7

5

4

4

-

3

4

-

Aerobic respiration (cyanide sensitive)

14

3

3

3

3

2

3

3

3

2

2

Aerobic respiration (cyanide insensitive)

8

2

2

2

2

2

-

-

-

-

-

2-keto glutarate dehydrogenase complex

3

2

2

2

2

-

-

-

2

-

-

N-acetylglucosamine degradation

3

3

3

3

3

3

3

3

3

3

3

Methylglyoxal pathway

12

2

2

2

2

2

2

-

-

-

-

Sphingolipid metabolism

8

-

-

-

-

-

-

-

-

2

-

Ergosterol biosynthesis

21

-

-

-

-

-

-

2

-

2

2

Biotin biosynthesis

4

4

4

-

3

-

-

2

-

-

-

NAD salvage pathway

4

-

-

-

2

-

-

-

-

-

-

Tetrapyrrole biosynthesis

4

2

2

2

2

-

-

-

2

-

-

Pantothenate and coA biosynthesis

11

2

2

2

2

2

2

2

2

2

2

Starch degradation

7

-

-

-

-

-

-

-

-

-

2

Lipid-linked oligosaccharide biosynthesis

8

-

-

-

2

2

3

2

3

2

-

Arginine degradation (arginase pathway)

5

2

2

2

-

-

-

2

2

2

2

Lysine biosynthesis

6

-

-

-

2

-

-

-

-

-

-

Superpathway of glycine biosynthesis

5

-

-

-

-

2

-

-

-

-

-

Biosynthesis of phe/tyr/trp

13

-

-

-

-

-

2

-

-

-

-

Superpathway of glycine biosynthesis

5

-

-

-

-

5

-

-

-

-

-

Acrylonitrile degradation

4

-

-

-

2(2T)

2(2T)

2(2T)

-

2(2T)

-

-

Galactose degradation

5

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

4(2D)

tRNA charging pathway

35

13(6D)

13(6D)

13(6D)

10(2D)

7(4D)

9(6D)

9(4D)

13(6D)

9(4D)

5(4D)

Fatty acid oxidation pathway

14

4(4D)

4(4D)

2(2D)

4(4D)

4(4D)

-

2(2D)

2(2D)

2(2T)

2(2T)

Glutathione-glutaredoxin redox reactions

9

5(3D, 3D)

5(2D,2T)*

6(3D,3T)

3(3T)

4(4T)

3(3T)

2(2T)

2(2T)

3(3T)

2(2D)

Isoleucine & phenylalanine degradation

12

2(2T)

2(2T)

-

-

-

-

-

-

-

-

Removal of superoxide radicals

7

2(2T)

2(2T)

2(2T)

-

-

-

-

-

-

-

  1. Superscript numerals in parenthesis refer to the numbers of genes that are either paralogs D or tandem duplicates T.
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