Table 2 Comparison of the regulation on protein and transcript level.
From: Integrative analysis of the heat shock response in Aspergillus fumigatus
Protein | PC of protein to transcript (no delay/best delay (best delay in minutes)) | SC of protein to transcript (no delay/best delay (best delay in minutes)) |
|---|---|---|
Chaperone | Â | Â |
AFUA_1G07440 (molecular chaperone Hsp70) | 0.48/0.52 (15) | 0.26/0.52 (15) |
AFUA_1G11180 (heat shock protein/chaperonin HSP78) | 0.44/0.52 (15) | 0.31/0.52 (15) |
AFUA_1G12610 (HSP 70 chaperone HSP88) | 0.72/0.72 (0) | 0.60/0.60 (0) |
AFUA_2G09290 (antigenic mitochondrial protein HSP60) | 0.33/0.86 (75) | 0.09/0.86 (75) |
AFUA_2G13040 (mitochondrial co-chaperone GrpE) | 0.80/0.80 (0) | 0.83/0.83 (0) |
AFUA_3G14540 (heat shock protein Hsp30/Hsp42) | -0.36/0.95 (105) | -0.51/0.89 (90) |
AFUA_4G10010 (Hsp90 co-chaperone Cdc37) | 0.18/0.76 (105) | -0.03/-0.03 (0) |
AFUA_5G04170 (molecular chaperone and allergen Mod-E/Hsp90/Hsp1) | 0.60/0.75 (15) | 0.14/0.58 (30) |
AFUA_5G07340 (DnaJ domain protein Psi) | -0.35/0.82 (75) | -0.09/0.96 (90) |
AFUA_7G01860 (heat shock protein (Sti1)) | 0.02/0.9 (90) | -0.09/0.96 (90) |
Cell wall and cytoskeleton | Â | Â |
AFUA_1G02550 (tubulin alpha-1 subunit) | -0.52/0.97 (60) | -0.43/0.98 (60) |
Transport | Â | Â |
AFUA_5G03690 (CRAL/TRIO domain protein) | -0.73/0.78 (60) | -0.77/0.88 (75) |
AFUA_6G07120 (nuclear movement protein NudC) | -0.24/0.68 (90) | -0.60/0.86 (90) |
Defence against oxidative and nitrosative stress | Â | Â |
AFUA_4G09110 (cytochrome c peroxidase Ccp1) | 0.76/0.94 (105) | 0.60/0.94 (105) |
AFUA_5G09910 (nitroreductase family protein) | -0.75/0.83 (105) | -0.71/0.43 (105) |
Signal transduction | Â | Â |
AFUA_1G05610 (protein phosphotase 2a 65 kd regulatory subunit) | -0.60/0.88 (90) | -0.54/0.96 (90) |
Carbohydrate metabolism | Â | Â |
AFUA_2G05910 (hexokinase Kxk) | -0.95/0.91 (90) | -0.83/0.96 (90) |
AFUA_2G10660 (mannitol-1-phosphate dehydrogenase) | -0.13/0.51 (15) | 0.03/0.57 (15) |
AFUA_3G08660 (isocitrate dehydrogenase Idp1) | -0.76/0.91 (90) | -0.77/0.93 (90) |
AFUA_4G11080 (acetyl-coenzyme A synthetase FacA) | -0.79/0.97 (90) | -0.71/0.93 (90) |
AFUA_6G10650 (ATP citrate lyase, subunit 1) | -0.450/0.94 (60) | -0.54/0.97 (60) |
Nitrogen metabolism | Â | Â |
AFUA_1G12840 (nitrite reductase NiiA) | -0.22/0.95 (30) | -0.20/0.83 (30) |
AFUA_2G11260 (3-isopropylmalate dehydratase) | -0.34/0.93 (105) | -0.37/0.94 (105) |
AFUA_2G13530 (bifunctional tryptophan synthase TRPB) | -0.85/0.85 (90) | -0.83/0.93 (75) |
AFUA_4G07360 (cobalamin-independent methionine synthase MetH/D) | -0.83/0.81 (75) | -0.83/0.96 (90) |
AFUA_4G07710 (pyruvate carboxylase) | -0.54/0.96 (90) | -0.49/0.93 (90) |
AFUA_4G10460 (homocitrate synthase) | -0.73/0.86 (75) | -0.60/0.89 (90) |
Protein biosynthesis/Translation | Â | Â |
AFUA_1G02030 (eukaryotic translation initiation factor 3 subunit EifCb) | -0.86/0.89 (75) | -0.89/0.88 (75) |
AFUA_6G12660 (40S ribosomal protein S10b) | -0.23/0.93 (90) | 0.09/0.86 (90) |
AFUA_7G05660 (translation elongation factor eEF-3) | -0.17/0.70 (105) | -0.03/0.60 (105) |
Transcription | Â | Â |
AFUA_1G15620 (DEAD box RNA helicase HelA) | -0.83/0.82 (75) | -0.94/0.86 (90) |
AFUA_3G08580 (glycine-rich RNA-binding protein) | 0.93/0.93 (0) | 0.94/0.94 (0) |