Functional and evolutionary correlates of gene constellations in the Drosophila melanogaster genome that deviate from the stereotypical gene architecture

Table 1 Genomic and functional correlates of gene constellations^a.

Group	Recombination rate (X-/Auto)	X/Autosomal linkage	*Sim*_RelAll_BM	*Sim*_RelBP_BM	*Sim*_RelMF_BM	*Sim*_RelCC_BM	Expression correlation
SG	2.782(± 0.923)/1.451(± 1.365)	155/680	0.165 (± 0.173)	0.165* (± 0.218)	0.101* (± 0.167)	0.141 (± 0.205)	0.027 (± 0.551)
5PP	2.755.(± 0.959)/1.646(± 1.292)	671/3501	0.326** (± 0.286)	0.289** (± 0.306)	0.182** (± 0.255)	0.258** (± 0.299)	0.278** (± 0.540)
EE	2.634(± 1.033)/1.645(± 1.270)	94/632*	0.217** (± 0.184)	0.211** (± 0.239)	0.133** (± 0.210)	0.196** (± 0.231)	0.154** (± 0.596)
5PI-EI	2.933*(± 0.859)/1.593(± 1.332)	104/538	0.114** (± 0.180)	0.171 (± 0.247)	0.113 (± 0.198)	0.085** (± 0.163)	0.086 (± 0.525)
COS	2.704(± 0.998)/1.676*(± 1.311)	582/2966	0.352** (± 0.323)	0.292** (± 0.330)	0.198** (± 0.286)	0.258** (± 0.329)	0.097** (± 0.578)
CSS	2.721(± 0.964)/1.706*(± 1.335)	142/589*	0.304** (± 0.300)	0.276** (± 0.320)	0.195** (± 0.290)	0.223** (± 0.296)	0.119** (± 0.581)
Genomic average ^b	2.742(± 0.968)/1.643(± 1.308)	1748/8906	0.165 (± 0.173)	0.166 (± 0.218)	0.101 (± 0.167)	0.141 (± 0.205)	0.027 (± 0.551)

^ac.f. Additional File 1 for data and Additional file 4 for a summary of sample sizes.
^bAverage values, except for the ratio of X- and autosomal genes, where the value provided should be considered the genome wide ratio.
* and ** indicate significant deviation from the genomic average at P-value ≤ 0.05 and P-value ≤ 0.001, respectively (Chi-square test or two-sided Mann-Whitney test, not corrected for multiple testing).

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