Name | Description | Biological functions/process1 | Type2 | FD3 |
---|---|---|---|---|
DEG highly-expressed in parenchyma vs. fat pad | ||||
   SPP1 | secreted phosphoprotein 1 (osteopontin) | Protein binding | Cyt | 22.1 |
   CXCL10 | chemokine (C-X-C motif) ligand 10 | Chemokine activity, chemotaxis | Cyt | 3.5 |
   PDGFA | platelet-derived growth factor alpha polypeptide | Actin cytoskeleton organization | GrF | 2.2 |
   DKK1 | dickkopf homolog 1 (Xenopus laevis) | Inhibition of Wnt signaling | GrF | 2.1 |
   NRG1 | neuregulin 1 | Cell-cell communication, murine mammary development | GrF | 2.0 |
   BDNF | brain-derived neurotrophic factor | Anti-apoptosis, axon guidance | GrF | 1.8 |
   NTF4 | neurotrophin 4 | Regulation of synaptic plasticity | GrF | 1.7 |
   ANGPT1 | angiopoietin 1 | Angiogenesis, signal transduction | GrF | 1.6 |
   IL7 | interleukin 7 | Anti-apoptosis, cell-cell signalling | Cyt | 1.6 |
   FGF7 | fibroblast growth factor 7 (keratinocyte growth factor) | Positive regulation of epithelial cell proliferation, signal transduction | GrF | 1.6 |
   LTA | lymphotoxin alpha (TNF superfamily, member 1) | TNF receptor binding, immune response | Cyt | 1.6 |
   IL1B | interleukin 1, beta | Immune response, chemotaxis, anti/pro-apoptosis | Cyt | 1.6 |
   CCL2 | chemokine (C-C motif) ligand 2 | Chemotaxis, immune response, endothelial cell proliferation | Cyt | 1.5 |
   CXCL14 | chemokine (C-X-C motif) ligand 14 | Chemotaxis, immune response | Cyt | 4.4 |
   CXCL9 | chemokine (C-X-C motif) ligand 9 | Chemotaxis, immune response | Cyt | 2.3 |
   VAV3 | vav 3 guanine nucleotide exchange factor | Metal ion binding, protein binding | Cyt | 2.2 |
   HDGF | hepatoma-derived growth factor | Cell proliferation, regulation of transcription, DNA-dependent | GrF | 1.9 |
   CXCL6 | chemokine (C-X-C motif) ligand 6 | Chemotaxis, immune response | Cyt | 1.9 |
   MDK | midkine (neurite growth-promoting factor 2) | Cell differentiation/proliferation, nervous system development | GrF | 1.7 |
DEG highly-expressed in fat pad vs. parenchyma | ||||
   ADIPOQ | adiponectin, C1Q and collagen domain containing | Negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of inflammation | GrF | 24.1 |
   FGF2 | fibroblast growth factor 2 (basic) | Chemotaxis, positive regulation of angiogenesis and epithelial cell proliferation | GrF | 3.5 |
   GRP | gastrin-releasing peptide | Signal transduction, hormone activity, neuropeptide signaling | GrF | 2.9 |
   NOV | nephroblastoma overexpressed gene | Insulin-like growth factor binding, regulation of cell growth | GrF | 2.5 |
   FGF8 | fibroblast growth factor 8 (androgen-induced) | Cell proliferation, signal transduction, induced by androgens in breast cancer cells | GrF | 1.9 |
   LEP | Leptin | Hormone activity, regulation of metabolic process | GrF | 1.9 |
   IL13 | interleukin 13 | Cell motion, cell-cell signaling, immune response | Cyt | 1.7 |
   JAG1 | jagged 1 (Alagille syndrome) | Angiogenesis, cell fate determination, regulation of cell proliferation, activation of Notch signaling pathway | GrF | 1.6 |
   IL1A | interleukin 1, alpha | Immune response, positive regulation of cytokine secretion, pro-angiogenesis | Cyt | 1.6 |
   CCL14 | chemokine (C-C motif) ligand 14 | Cellular calcium homeostasis, immune response, positive regulation of cell proliferation | Cyt | 1.9 |
   OGN | Osteoglycin | Protein binding | GrF | 1.8 |
   EDA | ectodysplasin A | Cell differentiation, immune response, positive regulation of NF-kappaB transcription | Cyt | 1.7 |
   CCL24 | chemokine (C-C motif) ligand 24 | Chemotaxis, immune response, cell-cell signaling | Cyt | 1.7 |
   CXCL2 | chemokine (C-X-C motif) ligand 2 | Chemotaxis, immune response | Cyt | 1.6 |
   CCL20 | chemokine (C-C motif) ligand 20 | Chemotaxis, immune response, cell-cell signalling | Cyt | 1.5 |