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Table 4 Identification of transcription factor binding sites (TFBSs) present in TFAP2A- modulated genes by over-represented DNA oligonucleotides.

From: Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes

TFAP2A-regulated genes

Over-represented oligo

TF

Target genes

p (Fisher test)

DOWN n = 157

CGGGC*

AP-2alpha, C-Rel, MYB, AMEF-2

22

1.20E-07

 

GAGCCGGC

 

27

1.48E-07

 

CCCGC*

OLF-1, AP-2alpha, Sp-1,TCF-1(P),EGR

38

7.76E-07

 

CCCGGC*

AP-2alpha, MTF-1

47

1.20E-06

 

CCCCGAGG*

AP-2alpha

51

4.57E-06

 

CGGCA*

AP-2alpha

57

7.08E-06

 

CCCATCCTA

 

64

1.17E-05

 

CGGCAGCC

 

65

1.51E-05

 

GCCCGC*

AP-2alpha

66

2.45E-05

 

CGGGTGCTC

 

70

2.75E-05

UP n = 107

AAGCGCG*

 

6

8.32E-06

 

GGGGACTAA

 

11

1.62E-05

 

AGACGTCT

 

16

2.04E-05

 

AAACAACAG*

 

21

4.27E-05

 

ACCCACGCG*

 

26

5.13E-05

 

CGGGGTAGA

 

29

5.89E-05

 

CCTGTTTCG*

 

33

6.92E-05

 

CCGGAG

 

40

7.08E-05

 

ACGGGTTCT

 

42

7.59E-05

 

CCGGAGGC

AP-2alpha

43

8.13E-05

  1. For each TF its consensus binding site sequence, abbreviated name, number of target genes and statistical enrichment values (Fisher-score) are reported. * conserved over-represented oligo
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BMC Genomics

ISSN: 1471-2164

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