Table 6 Identification of transcription factor binding sites (TFBSs) present in TFAP2A- modulated genes by MEME analysis.
From: Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
TFAP2A-regulated genes | MEME regular expression | TF | Target genes | MEME E-value |
|---|---|---|---|---|
DOWN n = 157 | [GA]CCTGTA[AG]TCCCAGC[TA][CA][CT]T[TC] | PITX2, CRX | 26 | 9.1E-162 |
| Â | AT[CT]CTCC[TC][GA]CCTC[AG]G | Â | 34 | 2.6E-058 |
| Â | T[CG][CG]A[GC][TA]CCAGCCTGG[GC]C[AG]AC | Â | 29 | 4.3E-104 |
| Â | AGG[TC]TGCAGTGAGC[CT]G[AT]GAT | Sp-1, AP-2apha, MAZ, TFII-I | 24 | 3.1E-085 |
| Â | GG[GA]GG[CA]GGGG[CGA][GC]GG[GA][GAC]G[GAC]GG | Â | 38 | 1.7E-056 |
| Â | GTGAGCCAC[CT][GA]CGCCCGGC[CT] | Â | 21 | 2.0E-049 |
UP n = 107 | CTCCC[AG]A[AG][GT][TA]GCTGGGA[TC]TA | MYOD, PITX2, CRX | 20 | 2.1E-126 |
| Â | GT[CT]TC[AG]C[TC][AC]TGT[TC][GA][CG]CCAGG | YY1, AP-2alpha | 22 | 1.5E-082 |
| Â | G[GC]GGCGG[GC]G[GC][CG]GG[GC]GG[CG]GG[GC] | Sp-1, AP-2alpha | 35 | 9.7E-062 |
| Â | [GT]TGTGTGTG[TC]G[TC][GA][TC]GTGTG[TG] | MYC | 9 | 3.2E-016 |
| Â | G[GC][TC]TCAAG[CT]GAT[TC]CTCC[TC]GC | NKX2-5 | 16 | 1.5E-049 |
| Â | CAGG[CT]G[TC]G[AC]GCCACC[GA]C[GA]CC | AREB6, AML1 | 19 | 7.7E-067 |
| Â | ATCT[CT][GA]GCTCACTGCA[AG]CCT | Â | 16 | 9.8E-048 |
| Â | TGGTCTCGA[TA]CTCCTGACCT | T3R, ER | 12 | 8.0E-032 |