Figure 2

Superfamily tree of PepP/PepQ/PepM members in LAB. Genome abbreviations can be found in "Methods". For each gene, the organism abbreviations are followed by GI codes. Homologs from two non-LAB strains are also included, CBO for Clostridium botulinum F str. Langeland and ECO for E. coli. Experimentally characterized genes are highlighted by the red dots. Green circles represent the speciation events, and red squares represent duplication events.