Table 1 Gene ontology analysis of genes expressed at higher levels in CD34+ cells
Molecular Function | # genes | p-value |
|---|---|---|
Nucleic acid binding | 440 | 1.41E-24 |
Transcription factor | 328 | 6.13E-20 |
Zinc finger transcription factor | 173 | 3.54E-16 |
KRAB box transcription factor | 129 | 4.95E-16 |
Synthase and synthetase | 63 | 1.93E-13 |
Transferase | 154 | 1.13E-11 |
Synthase | 37 | 1.97E-09 |
Methyltransferase | 34 | 5.45E-05 |
Oxidoreductase | 93 | 9.25E-05 |
Hydrolase | 105 | 5.66E-04 |
Lyase | 32 | 1.23E-03 |
Kinase | 97 | 1.43E-03 |
Transcription cofactor | 35 | 2.58E-03 |
Synthetase | 24 | 3.41E-03 |
Other miscellaneous function protein | 68 | 3.98E-03 |
Nuclease | 36 | 1.19E-02 |
DNA-directed DNA polymerase | 10 | 1.30E-02 |
Translation initiation factor | 17 | 1.81E-02 |
Select regulatory molecule | 145 | 2.39E-02 |
DNA helicase | 19 | 2.91E-02 |
Acetyltransferase | 20 | 2.99E-02 |
Ligase | 65 | 3.82E-02 |
Aminoacyl-tRNA synthetase | 12 | 3.89E-02 |