Tir
| MMU | | F21,7 | F6 AIL2, | F12 AIL3 |
|---|
Tir 1 | 17 | Map Location (cM) | ~14 | 17.9 cM | ND |
| | | CI (cM) | ND | 0.9 cM | ND |
| | | Effect (days) | 33.5 | 38.8 | 30.0 |
| | | PVar (%) | 11.8 | 19.6 | ND |
Tir2 | 5 | Map Location (cM) | ~20 | 45 | 41 |
| | | CI (cM) | ND | 12 | 1 |
| | | Effect (days) | 22 | 14.7 | 8.9 |
| | | PVar (%) | 5.3 | 3.3 | 4.5 |
Tir 3a | 1 | Map Location (cM) | | 59.7 | 67 |
| | | CI (cM) | | 1.8 | 6 |
| | | Effect (days) | | 14.45 | 11.33 |
| | | PVar (%) | | 2.6 | 6.7 |
Tir 3b | 1 | Map Location (cM) | 73 | 73 | 76 |
| | | CI (cM) | ND | 10 | 7 |
| | | Effect (days) | 32 | 17.3 | 11.3 |
| | | PVar (%) | 8.9 | 4.1 | 7.9 |
Tir 3c | 1 | Map Location (cM) | | 94 | 86 |
| | | CI (cM) | | 8 | 2 |
| | | Effect (days) | | 13.4 | 12.1 |
| | | PVar (%) | | 2.3 | 8.6 |
- The most likely map locations (cM) are given as distances in cM from the telomere. Effect, difference between alternative homozygous genotypes (additive effect) in days4; CI, 95% confidence intervals for QTL map location in cM5; PVar, proportion of phenotypic variance explained by each of the Tir loci6.
- 1 Data from [7]; Mean of BALB/cJ × C57BL/6J and A/J × C57BL/6J.
- 2 Data from [16, 19].
- 3 Generated from A/J × C57BL/6J and fixed for MMU17 A/J (susceptible) allele.
- 4 For F12 AIL, dominance effects are Tir 2, 4.5; Tir 3a, -1.2; Tir 3b, -5.7; Tir 3c, -5.0.
- 5 For F12 AIL, flanking markers defining the most likely interval containing the QTL are: Tir 2, D5MIT258-58; Tir 3a, D1MIT94-140; Tir 3b, D1MIT288-105; Tir 3c, D1MIT107-58.
- 6 For F12 AIL, LOD scores are: Tir 2, 3.81; Tir 3a, 4.49; Tir 3b, 3.48; Tir 3c, 3.18.
- 7 Tir 3 mapped as a single locus in the F2 experiment.
