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Archived Comments for: The Escherichia coli K-12 ORFeome: a resource for comparative molecular microbiology

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  1. YgjD - YeaZ - YjeE protein-protein interactions

    Peter Uetz, VCU

    25 June 2015

    As an example (and control) of how the ORFs of this study can be used to study protein-protein interactions, we somewhat arbitrarily selected 3 proteins: YgjD, YeaZ, YjeE, which had been purified in a complex before. Unfortunately, this was not mentioned in the abstract.

    However, these interactions turn out to be quite interesting and several groups have studied them independently. Most recenlty, Zhang et al. presented crystal structures of YgjD–YeaZ–YjeE from E. coli and their interactions in 

    http://nar.oxfordjournals.org/content/early/2015/01/10/nar.gku1397.full

    Competing interests

    None

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