| Liver-hypo T-DMRs | Brain-hypo T-DMRs | Heart-hypo T-DMRs |
---|---|---|---|
Various mitochondrial functions | Â | Â | Â |
   Metabolism | Abat, Acsl5, Oat, etc | Dmgdh, Mthfd1, Star, etc | Cpt1b, Efta, Pdk4, etc |
   Respiratory chain | Atp5o, Ndufb2, etc | Atp5l, Cox6, Ndufs8, etc | Atp5l, Ndufs4, Sdhc, etc |
   TCA cycle | Dlst | Aco2, Dlst | Ogdh |
   Detoxification | Gsr, Hagh, Mgst1, Tst | Gstk1 |  |
Tissue-specific mitochondrial functions | Otc, Lrpprc | Â | Â |
Protein sorting | Immp1l | Tomm7 | Â |
Regulation of mitochondrial morphology | Â | Mfn1, Prelid1 | Â |
Regulation of mtDNA | Peo1 | Â | Â |
Translation of mtDNA-encoded proteins | Lrpprc | Mtif2, Mtif3 | Mrrf, Tufm |