Figure 3

Figures 3A-C compare the power of KWII (green bars) to that of MDR (red bars), RPM (orange bars) and blue for logistic regression at α-values of 0.001 and 0.0001. The sample size was 1200. Figure 3A corresponds to Interaction 1, Figure 3B corresponds to Interaction 3 and Figure 3C represents the power to detect all three interactions. The penetrance matrices for the combinations of SNP pairs involved in Interactions 1, 2 and 3 are shown in Table 4. The bar corresponding to MDR in Figure 3C is apparently not visible because the power was low.