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Table 4 Penetrance tables for comparing KWII to the other four competing methods.

From: Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity

Interaction 1

SNP(1) with SNP(2)

Interaction 2

SNP(5) with SNP(6)

Interaction 3

SNP(9) with SNP(10)

 

BB

Bb

bb

 

BB

Bb

bb

 

BB

Bb

bb

AA

0.02

0.053

0.02

AA

0.02

0.053

0.02

AA

0.035

0.035

0.042

Aa

0.053

0.02

0.053

Aa

0.053

0.02

0.053

Aa

0.035

0.038

0.035

aa

0.02

0.053

0.02

aa

0.02

0.053

0.02

aa

0.042

0.035

0.035

  1. The overall disease prevalence is K p = 0.037. Only pairwise penetrances for SNP directly involved in Interactions 1, 2, and 3 are shown. The penetrance values for Interaction 1 and Interaction 2 are from [16] whereas those for Interaction 3 are from [2].