Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom

BMC Genomics

Table 1 The presence or absence of Tor pathway components in non-pathogenic and pathogenic fungal lineages

		Ascomycota		Basidiomycota	Zygomycota			Chytridiomycota		Microsporidia
		Sc	Sp	Po	Mc	Ro	Pb	Bd	Spu	spp.
TORC1	Tor1	+	+	+	+	+	+	+	+	-
	Kog1	+	+	+	+	+	+	+	+	-
	Tco89	+	-	-	-	-	-	-	-	-
	Lst8	+	+	+	+	+	+	+	+	-
TORC2	Tor2	+	+	+	-	-	-	+	-	-
	Lst8	+	+	+	+	+	+	+	+	-
	Avo1	+	+	+	+	+	+	+	+	-
	Avo2	+	-	-	+	+	+	+	+	-
	Avo3	+	+	+	+	+	+	+	+	-
	Bit61	+	-	-	-	-	-	-	-	-
Upstream	Tsc1	-	+	+	+	+	+	-	+	-
	Tsc2	-	+	+	+	+	+	+	+	-
	Rhb1	+	+	+	+	+	+	+	+	-
	Ego1	+	-	-	-	-	-	-	-	-
	Ego3	+	-	-	-	-	-	-	-	-
	Gtr1	+	+	+	+	+	+	+	+	-
	Gtr2	+	+	+	+	+	+	+	+	-
	Vam6	+	+	+	+	+	+	+	+	-
Downstream	Sit4	+	+	+	+	-	+	+	+	-
	Tap42	+	+	+	+	+	+	+	+	-
	Sch9	+	+	+	-	-	-	+	+	-
	Ypk2	+	+	-	-	+	-	-	-	-

The presence or absence of Tor pathway components is indicated by + or -, respectively. Abbreviations: Sc = S. cerevisiae, Sp = S. pombe, Po = P. ostreatus, Mc = M. circinelloides, Ro = R. oryzae, Pb = P. blakesleeanus, Bd = B. dendrobatidis, Spu = S. punctatus.

ISSN: 1471-2164