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Table 2 Genes up-regulated ≥3-fold by BF/S+L/Ep or cyotpiloyne at 4 hours.

From: Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling

   

Gene Expresion Ratio (Test + LPS): LPS only

 

Gene Symbol

Gene ID

shikonin

emodin

cytopiloyne

BF/S+L/Ep

Cytokines

CSF1

1435

0.91

1.69

3.54

3.12

 

IL5

3567

0.87

1.35

2.77

3.01

 

TNFSF14

8740

1.01

1.36

2.67

3.03

Chemotaxis & Cell Migration

CCR1

1230

0.87

1.3

2.91

3.09

 

CCR8

1237

0.78

1.48

2.76

3.14

 

ITGAX

3687

1.08

1.38

2.88

3.19

 

CXCR4

7852

1.21

1.63

3.33

2.63

 

MADCAM1

8174

0.82

1.45

3.04

3.39

Inflammatory Responses

CD14

929

0.9

1.56

3.24

3.26

 

MAP2K4

6416

1.25

1.4

2.59

3.56

 

TLR3

7098

0.91

1.33

2.35

3.06

 

IL1R2

7850

0.91

1.49

2.64

3.13

 

TNFRSF10D

8793

0.84

1.4

2.86

3.28

 

TBX21

30009

0.66

1.34

2.89

3.2

Other

SHC1

6464

0.89

1.22

2.4

3.2

 

ADAMDEC1

27299

1.14

1.79

2.71

3