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Figure 1 | BMC Genomics

Figure 1

From: Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma

Figure 1

Representative Gene Ontology associations and functional interactions between genes in the senescence scoring signature. The figure illustrates the cooperation between diverse processes including cell proliferation, chromatin remodelling and stress/inflammatory responses in the senescence phenotype. Blue and grey boxes represent parent and child GO processes, respectively. Red and green arrows represent negative and positive regulation, respectively. Mechanism: IE, influence on expression; B, binding; C, cleavage.

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BMC Genomics

ISSN: 1471-2164

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