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Table 4 Results from GSEA for breast cancer in FF samples. The following 26 gene sets (GO-terms) were common in all the four lists shown in figure-4(v)

From: Analyses and interpretation of whole-genome gene expression from formalin-fixed paraffin-embedded tissue: an illustration with breast cancer tissues

Gene Set Description

# of Genes

ES*

NES**

p-value

metalloexopeptidase activity

37

0.5273

1.6927

0.0000

transforming growth factor beta receptor signaling pathway

67

0.4600

1.6388

0.0192

fatty acid metabolic process

116

0.3829

1.5961

0.0000

sterol transport

26

0.4747

1.5879

0.0417

cholesterol transport

25

0.4770

1.5853

0.0208

vitamin metabolic process

22

0.5190

1.5649

0.0204

regulation of insulin secretion

26

0.4652

1.5559

0.0000

regulation of biomineral formation

26

0.4641

1.5288

0.0000

muscle cell differentiation

40

0.4888

1.5192

0.0408

vitamin binding

121

0.3420

1.4857

0.0385

regulation of blood vessel size

43

0.4805

1.4810

0.0408

regulation of tube size

43

0.4805

1.4810

0.0408

BMP signaling pathway

36

0.5195

1.4783

0.0426

regulation of cell proliferation

171

0.3540

1.4709

0.0200

glucose metabolic process

42

0.3829

1.4667

0.0217

blood circulation

46

0.4345

1.4544

0.0204

branching morphogenesis of a tube

55

0.4291

1.4160

0.0208

regulation of hormone secretion

36

0.3898

1.4101

0.0385

magnesium ion binding

418

0.2887

1.3951

0.0000

GTPase binding

85

0.3092

1.3766

0.0000

response to drug

81

0.3105

1.3461

0.0364

carbohydrate binding

301

0.2844

1.3073

0.0204

small GTPase binding

80

0.2944

1.2867

0.0364

protein dimerization activity

433

0.2449

1.2408

0.0196

negative regulation of DNA metabolic process

23

-0.4876

-1.5264

0.0217

nucleosome

87

-0.6222

-1.5847

0.0417

  1. *ES: Enrichment score, **NES: normalized enrichment score