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Figure 10 | BMC Genomics

Figure 10

From: The human G93A-SOD1 mutation in a pre-symptomatic rat model of amyotrophic lateral sclerosis increases the vulnerability to a mild spinal cord compression

Figure 10

Immunoresponse in spinal cord caudal to compression epicenter. ED1 immunopositive cells (macrophages) were detected in the spinal cord ventral horn of WT (A) and G93A-SOD1 (B) in sections caudal to compression epicenter 7 days post-injury. Quantification showed an elevated but non-significant increase in ED1 immunopositive cells in G93A-SOD1 compared to WT spinal cord (P = 0.08, C). OX42 immunopositive cells (activated microglia) were detected in the spinal cord ventral horn of WT (D) and G93A-SOD1 (E) in sections caudal to compression epicenter 7 days post-injury. Quantification showed no significant difference in OX42 immunopositive cells in spinal cord of both groups (P = 0.76, F). ns: non-significant. Scale bar = 200 μm.

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BMC Genomics

ISSN: 1471-2164

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