Identification of genes for small non-coding RNAs that belong to the regulon of the two-component regulatory system CiaRH in Streptococcus

Table 1 Similarity of CiaRH proteins of various streptococci to S. pneunomiae CiaRH proteins.

Streptococcus	CiaR^a	CiaH^b	CiaR recognition helix^c
			VVEVYVSKVRKKL ^d
S. mitis B6	99	86	VVEVYVSKVRKKL
S. oralis Uo5	96	83	VVEVYVSKVRKKL
S. sanguinis SK36	88	60	VVEVYVSK I RKKL
S. agalactiae NEM316	88	51	VVEVYVSKVRKKL
S. dysgalactiae subsp. equisimilus GGS_124	84	50	VVEVYVSK I RKKL
S. equi subsp.equi 4047	80	50	VVEVYVSK I RKKL
S. equi subsp. zooepidemicus MGCS10565	80	51	VVEVYVSK I RKKL
S. gallolyticus UCN34	81	51	VVEVYVSK I RKKL
S. gordonii str. Challis substr. CH1	89	65	VVEVYVSK I RKKL
S. mutans UA159	89	55	VVEVYVSK I RKKL
S. pyogenes MGAS315	84	51	VVEVY I SK I RKKL
S. suis 05ZYH33	88	48	VVEVYVSK I RKKL
S. thermophilus CNRZ1066	86^e	47^e	VVEVYVSK I RKKL
S. uberis 0140J	84	51	VVEVY I SK I RKKL
	OmpR	E. coli	SID V QI S RL R RMV

^a,b Similarity is given in% identical residues of S. pneumoniae R6 CiaR and CiaH, respectively.
^c The CiaR recognition helix was identified according to the OmpR family comparison defining DNA binding sites [37].
^d The recognition helix of S. pneumoniae R6 CiaR is shown for comparison. Residues deviating from CiaR R6 are underlined.
^e ciaR is interupted by a stop codon and was artificially fused for comparison. ciaH is interrupted by two frame shifts and was artificially fused for comparison.

ISSN: 1471-2164