Figure 9From: Post-transcriptional regulation in the myo1Δ mutant of Saccharomyces cerevisiaeDiagram of proposed mRNA translation control pathways. Translating mRNAs are normally associated with eIF4F, which ultimately leads to the initiation of protein synthesis. In a process that can be mediated by stress sensors in the yeast cell plasma membrane, non-translating mRNAs may become associated with P-bodies that may lead to either mRNA decay or temporary sequestration of mRNAs for subsequent retrieval to the translating mRNA pool after adaptation to the stress. A novel eIF2α-P-containing complex is proposed as an alternative pathway for sequestration of non-translating RP mRNAs (blue-lined box). Asterisks identify immunoprecipitated proteins that were associated to translating or non-translating mRNAs in this study.Back to article page