From: Post-transcriptional regulation in the myo1Δ mutant of Saccharomyces cerevisiae
Initiation Factor/Gene Names | Function (http://www.yeastgenome.org) | Fold Change in Microarray (p≤0.01) | Fold Change by Real Time RT-PCR (± s.d.) |
---|---|---|---|
eIF1Ad (TIF11) | Forms a complex with Sui1p (eIF1) and the 40 S ribosomal subunit and scans for the start codon | -2.41 | -2.52 ± 0.42 |
eIF2γ (GCD11) | Identification of the start codon | -1.43 | -1.26 ± 0.21 |
eIF2Bβ (GCD7) | Guanine-nucleotide exchange factor for eIF2 | -1.29 | -1.38 ± 0.27 |
eIF5 (TIF5) | GTPase-activating protein mediates hydrolysis of ribosome-bound GTP | -1.25 | -1.60 ± 0.47 |
eIF4A (TIF2) | RNA helicase | -1.32 | -2.14 ± 0.50 |
eIF3β (PRT1) | Binding of mRNA and Met- tRNAi to ribosomes | -1.39 | -1.87 ± 0.10 |