Figure 5

Features of putative tyrosine kinases of Phytophthora. A, Maximum likelihood tree incorporating the TKs from P. infestans (Pi prefix) and their orthologs from P. ramorum (Pr) and P. sojae (Ps). Also included are three representatives of each of the P. infestans TKL, AGC, STE, CAMK, CK1, and CMGC groups, which are shown in collapsed branches to conserve space. The analysis also incorporated 60 metazoan TKs; to ensure that diverse TKs were analyzed, these included representatives of clades 1 to 20 as defined in a previous study [1]. Numbers at nodes are aLRT values from PhyML. B, Sequences of kinase subdomains VIb and VIII. Shown are relative amino acid frequencies for the predicted Phytophthora TKs (Phy; includes orthologs from P. infestans, P. ramorum, P. sojae), along with human TKs. Also illustrated are the amino acid frequencies within those domains in P. infestans and human TKLs.