Figure 3

C. botulinum ATCC 3502, ATCC 19397, and Hall strains genome alignment. The alignment display is organized into one horizontal "panel" per input genome sequence. Each genome's panel contains the name of the genome sequence, a scale showing the sequence coordinates for that genome, and a single black horizontal center line. All the blocks lie above the center line, which indicates that the aligned regions are in the forward orientation relative to the first genome sequence. Colored blocks in the first genome are connected by lines to similarly colored blocks in the second and third genomes. These lines indicate which regions in each genome are homologous and internally free from genomic rearrangement. There are only four blocks (1 to 4) from each genome. ATCC 3502 (top panel) and ATCC 19397 (middle panel) have the same block arrangements, while, in Hall (bottom panel), the positions of blocks 2 and 3 are switched. Inside each block, areas that are completely white were not aligned and contain sequence elements specific to a particular genome. Numbers in white inside the blocks indicate the block numbers.