Table 1 Non-randomly distributed superfamilies in E. coli and yeast MCL-GO complexes.
From: Comparative evolutionary analysis of protein complexes in E. coli and yeast
| Â | Superfamily | Frequency | Function | Species distribution |
|---|---|---|---|---|
E. coli | Â | Â | Â | Â |
| Â | NAD(P)-binding Rossmann-like Domain (3.40.50.720) | 73 | Oxidoreductase activity in a wide variety of processes | Universal |
Yeast | Â | Â | Â | Â |
| Â | RNA binding (2.30.30.100) | 11 | RNA binding/splicing | Universal |
| Â | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 (3.60.20.10) | 18 | Ubiquitin-mediated endopeptidase activity | Universal |
| Â | Quinoprotein amine dehydrogenase (2.130.10.10) | 68 | Wide range of activities including protein synthesis | Universal |
| Â | Protein tyrosine phosphatase superfamily (3.90.190.10) | 12 | Dephosphorylation in signalling pathways | Eukaryotic |
| Â | Ribosomal Protein (3.30.1370.10) | 4 | Binding activity in a variety of processes | Universal |
| Â | Ubiquitin-like superfamily (3.10.20.30) | 5 | TCA cycle | Universal |