Figure 1
From: An integrated functional genomic study of acute phenobarbital exposure in the rat
Liver histopathology. Liver histology. Upper panel: light microscopy image of hematoxylin and eosin stained liver tissue from control (A) and PB treated (B) animals. Livers from PB treated animals show centrilobular hypertrophy, compression of the periportal areas and eosinophilc appearance. Lower panel: electron microscopy images of control (C) and PB treated livers (D, E & F). PB treated livers showed dispersion of organelles and proliferation of the smooth endoplasmic reticulum.