Table 2 Predictive performance of classifiers constructed using single sequence features.
From: Sequence feature-based prediction of protein stability changes upon amino acid substitutions
Features | AC (%) | SN (%) | SP (%) | ST (%) | MCC | ROC AUC |
|---|---|---|---|---|---|---|
H | 75.88 | 71.62 | 77.79 | 74.70 | 0.4728 | 0.8237 |
K | 73.29 | 73.90 | 73.02 | 73.46 | 0.4402 | 0.7925 |
M | 68.06 | 73.52 | 65.62 | 69.57 | 0.3629 | 0.7480 |
P | 75.94 | 71.24 | 78.04 | 74.64 | 0.4718 | 0.8234 |
Co | 70.18 | 71.62 | 69.53 | 70.58 | 0.3838 | 0.7586 |
A | 76.41 | 74.29 | 77.36 | 75.82 | 0.4904 | 0.8206 |
B | 78.18 | 74.48 | 79.83 | 77.15 | 0.5199 | 0.8503 |
C | 72.18 | 71.05 | 72.68 | 71.86 | 0.4116 | 0.7847 |
Aa | 79.12 | 76.57 | 80.26 | 78.41 | 0.5431 | 0.8459 |
Bu | 82.06 | 75.62 | 84.94 | 80.28 | 0.5919 | 0.8777 |
S1 | 69.82 | 70.86 | 69.36 | 70.11 | 0.3756 | 0.7754 |
S2 | 70.24 | 72.19 | 69.36 | 70.78 | 0.3875 | 0.7665 |
S3 | 82.53 | 72.19 | 87.15 | 79.67 | 0.5922 | 0.8835 |
F | 61.41 | 63.62 | 60.43 | 62.02 | 0.2226 | 0.6728 |
R | 66.47 | 65.14 | 67.06 | 66.10 | 0.3008 | 0.7140 |
Mc | 78.35 | 73.52 | 80.51 | 77.02 | 0.5202 | 0.8417 |
No | 69.82 | 74.86 | 67.57 | 71.22 | 0.3944 | 0.7656 |
Rf | 62.06 | 73.71 | 56.85 | 65.28 | 0.2831 | 0.6889 |
Rm | 75.94 | 69.90 | 78.64 | 74.27 | 0.4672 | 0.8118 |
Tt | 83.59 | 66.48 | 91.23 | 78.86 | 0.6035 | 0.8704 |