Investigation gene and microRNA expression in glioblastoma

BMC Genomics

Table 2 22 MicroRNAs related to glioblastoma/ GBM/ Neuroblastoma

miRNA	P-value	AvgTumor	AvgNorm	Exp	Disease	Ref.
hsa-mir-21	3.08E-24	-0.253536	-4.15408	up	GBM	[14,15,16]
hsa-mir-23a	1.45E-16	0.0400785	-1.75999	up	GBM	[14]
hsa-mir-93	5.54E-12	0.0928069	-1.32487	up	NB	[17]
hsa-mir-25	1.85E-11	-0.278892	-1.7816	up	GBM	[14]
hsa-mir-155	1.40E-10	0.2248781	-1.32519	up	GBM	[16]
hsa-mir-92	2.52E-08	-0.089368	-1.30258	up	NB	[17]
hsa-mir-210	1.74E-07	-0.203768	-1.89154	up	GBM	[16]
hsa-mir-130a	3.84E-07	-0.024653	-0.83686	up	GBM	[14]
hsa-mir-106a	1.38E-06	0.0641864	-1.04192	up	NB	[17]
hsa-mir-17-5p	2.03E-06	0.0488078	-0.97014	up	NB	[17,18]
hsa-mir-323	5.78E-36	0.1500566	1.345004	down	GBM	[16]
hsa-mir-137	1.86E-31	0.5176077	3.537668	down	GBM	[16]
hsa-mir-128a	5.47E-26	0.041749	2.428222	down	GBM	[16]
hsa-mir-154*	7.62E-23	0.1359234	0.978151	down	GBM	[16]
hsa-mir-153	1.06E-21	0.0969089	0.406899	down	GBM	[16]
hsa-mir-132	6.84E-21	0.0656709	1.852984	down	GBM	[16]
hsa-mir-7	2.53E-18	0.6340624	3.431225	down	GBM	[19]
hsa-mir-124a	1.76E-17	-0.399441	4.758568	down	GBM	[16]
hsa-mir-133b	1.36E-11	-0.00609	0.559222	down	GBM	[16]
hsa-mir-29b	1.42E-10	0.2074092	1.923726	down	GBM	[16]
hsa-mir-149	2.87E-08	0.1160284	1.636419	down	GBM	[16]
hsa-mir-133a	9.15E-08	0.0038872	0.398482	down	GBM	[16]

Exp means whether the expression pattern of microRNA is up-regulated or down- regulated, comparing the average expression value in tumor tissues(AvgTumor) and average expression value in normal tissues(AvgNorm). GBM: Glioblastoma multiforme, NB: neuroblastoma.

ISSN: 1471-2164