Figure 5
From: Evolutionary patterns of amino acid substitutions in 12 Drosophila genomes
Rates and radicality of amino acid substitution vs. expression level and ubiquity. Relationship between relative substitution rate (Ka/Ka; A, C) and mean absolute change of polarity (|ΔP|; B, D) and log mean gene expression rate in whole fly (A, B) and coefficient of variation of expression rate across larval and adult tissues (C, D). Expression data from [22]. Solid lines: regressions significant at P<0.0001; dashed lines: regression without significant terms (shown for a comparison). Second-degree polynomial regression lines are shown when the quadratic term is significant, otherwise a linear regression is used.